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Monte Carlo simulation results for anaemia detection in the skin

Version 2 2020-01-20, 08:27
Version 1 2020-01-14, 10:30
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posted on 2020-01-20, 08:27 authored by Akhil Kallepalli, David JamesDavid James
This research was presented at SPIE Photonics West 2020 (February 2020) with the article titled: Quantification and influence of skin chromophores for remote detection of anemic conditions

(https://doi.org/10.1117/12.2545784)

Monte Carlo simulations were performed using Virtual Tissue Simulator (VTS) and Monte Carlo Command Line (MCCL) tools. The target was a two-layer model of the epidermis and dermis layers of the skin.

The optical attenuation properties quantifying the absorption and scattering in these layers are set according to two parameters:
- Amount of melanin in the epidermis
- Amount of haemoglobin in the blood-perfused dermis

The optical models are simulated at six wavelengths for 6 skin types (Fitzpatrick's scale) and two blood conditions, healthy and anaemic. This results in a total of 72 simulations

The simulation calculates the optical interaction of 106 photons with the various combinations of optical properties. The resulting outputs show the absorption and fluence in the tissue model, and reflected and transmitted energy.

History

Authoriser (e.g. PI/supervisor)

d.james@cranfield.ac.uk