Monte Carlo simulation results for anaemia detection in the skin Akhil Kallepalli David James 10.17862/cranfield.rd.11317187.v2 https://cord.cranfield.ac.uk/articles/figure/Monte_Carlo_simulation_results_for_anaemia_detection_in_the_skin/11317187 <div><div><b>This research was presented at SPIE Photonics West 2020 (February 2020) with the article titled: </b><b>Quantification and influence of skin chromophores for remote detection of anemic conditions </b></div><div><b><br></b></div><div><b>(https://doi.org/10.1117/12.2545784)</b></div></div><div><br></div>Monte Carlo simulations were performed using Virtual Tissue Simulator (VTS) and Monte Carlo Command Line (MCCL) tools. The target was a two-layer model of the epidermis and dermis layers of the skin. <div><br></div><div>The optical attenuation properties quantifying the absorption and scattering in these layers are set according to two parameters:</div><div>- Amount of melanin in the epidermis </div><div>- Amount of haemoglobin in the blood-perfused dermis</div><div><br></div><div>The optical models are simulated at six wavelengths for 6 skin types (Fitzpatrick's scale) and two blood conditions, healthy and anaemic. This results in a total of 72 simulations</div><div><br></div><div>The simulation calculates the optical interaction of 10<sup>6</sup> photons with the various combinations of optical properties. The resulting outputs show the absorption and fluence in the tissue model, and reflected and transmitted energy. </div> 2020-01-20 08:27:57 Monte Carlo computer simulations Skin anatomy anaemia chromophores absorption properties Scattering Properties photon transport haemoglobin concentration Hematocrit (HCT) erythrocyte concentration Simulation and Modelling Applied Physics Human Biophysics Biological Physics Medical Physics